Pathological types of breast cancer

Breast carcinomas can be found in two main forms depending on their origin. Approximately ninety percent originate from the ductal epithelium. The remaining ten percent, in the cells of the glandular acini. The first type, moreover, can present in various forms that are usually classified as subtypes, with different types of pathological, macroscopic and microscopic features that distinguish them. The classification can be presented as follows:

Distribution:

• External upper quadrant: 50%;
• Subbarian region: 20%;
• Remaining Quadrants: 10%;
• Multicentricity and possible bilaterality.

Types of breast cancer

Non-invasive tumors

Circular rate of incidence and prognosis of the types of histopathological breast cancer.

• Lobulillar carcinoma 'in situ': multicentricity in 70% and bilaterality in 40% of cases. Lobulillos are distended and filled completely by small, round cells with pleomorphism in the cellular nucleus and occasional mytosis and necrosis.
• Carcinoma ductal 'in situ' or intraductal carcinoma: malignant cells limited only to the epithelium respecting the basal membrane formed by preserved myoepithelial cells, but can be spread by the system of breast ducts. Subtypes:
  • Comedocarcinoma
  • Paget nipple disease: affects nipple epidermis and areola by neoplastic cells causing a nipple eczema. Over time, it is associated with cancer in situ underlying or deep infiltrating ductal cancer.
  • Carcinoma 'in situ' cribiforme
  • Carcinoma 'in situ' micropapilar
  • In situ carcinoma with lobular cancer

Invading or infiltrating tumors

• Introductory lobular carcinoma: occurs in 5-10% of cases, often multicentric and bilateral, monomorphic small cells that tend to form rows of a single cell.
• Infiltering ductal carcinoma: the most frequent (65-85%), miscircumscribed mass, lasts with radiated ductals within fat and areas of necrosis, bleeding and cystic degeneration.
  • Medular carcinoma
  • Carcinoma Papilar
  • Coloid carcinoma
  • Tubular carcinoma
  • Carcinoma Escirro
  • Inflammatory carcinoma
  • Multifocal carcinoma
  • Multicentric carcinoma
  • Metaplastic carcinoma
    • Fusiform cell carcinoma
    • Squamous cell carcinoma of ductal origin
    • Carcinosarcoma
    • Matrix production carcinoma
    • Metaplastic carcinoma with osteoclastic giant cells